Published: Estimating VO2peak in 18-90 Year-Old Adults: Development and Validation of the FitMáx©-Questionnaire

Hits: 129
  • Publication status: Gepubliceerd
  • Type of study: Clinimetrics
  • Journal: Dovepress - International Journal of General Medicine

  •  

    Papen-Botterhuis, N. ORCID iD

    Molenaar, C. ORCID iD

    Regis, M. ORCID iD

    Timmers, T. ORCID iD

    Pol van de - Franse, L ORCID iD

    Savelberg, H. ORCID iD

    Schep, G. ORCID iD

  • Affiliations: Eindhoven University of Technology, Maastricht University, Máxima Medical Centre, The Netherlands Cancer Institute, Tilburg University
  • Population: Healthy Subjects, Oncology, Cardiac, Pulmonary
  • DOI: https://doi.org/10.2147/IJGM.S355589
  • PMID: 35411174
  • BibTex: 
      
@article{Meijer2022FitMax,
  author  = {Renske Meijer and Martijn van Hooff and Nicole E. Papen-Botterhuis and Charlotte J. L. Molenaar and Marta Regis and Thomas Timmers and Lonneke V. van de Poll-Franse and Hans H. C. M. Savelberg and Goof Schep},
  title   = {Estimating VO₂peak in 18–90 Year-Old Adults: Development and Validation of the FitMáx©-Questionnaire},
  journal = {International Journal of General Medicine},
  volume  = {15},
  pages   = {3727--3737},
  year    = {2022},
  doi     = {10.2147/IJGM.S355589},
  url     = {https://doi.org/10.2147/IJGM.S355589}
}

Purpose: Cardiorespiratory fitness (CRF) plays an essential role in health outcomes and quality of life. However, it is often not assessed nor estimated. Objective CRF assessment is costly, labour intensive and not widely available. Patient-reported outcome measures estimate CRF more cost-efficiently, but current questionnaires lack accuracy. The aim of this study is to develop a new self-reported questionnaire to estimate CRF.

Materials and methods: The FitMáx©-questionnaire, consisting of only three questions assessing walking, stair climbing, and cycling capacity, was compared with the commonly used Duke Activity Status Index (DASI) and Veterans Specific Activity Questionnaire (VSAQ). These questionnaires were compared to peak oxygen uptake (VO2peak) as measured with cardiopulmonary exercise testing. This study included 759 cardiac, pulmonary and oncologic patients and healthy persons aged 18‒90.

Results: FitMáx© strongly correlated (r = 0.94 (0.92‒0.95) SEE = 4.14 mL∙kg-1∙min-1) with measured VO2peak. Bias between predicted and measured VO2peak was -0.24 (-9.23‒8.75; 95% limits of agreement) mL·kg-1·min-1. The FitMáx© scored superiorly on correlation and SEE compared with the DASI and VSAQ, r = 0.75 (0.68‒0.80) SEE = 4.62 mL∙kg-1∙min-1 and r = 0.87 (0.83‒0.90) SEE = 6.75 mL∙kg-1∙min-1, respectively.

Conclusion: FitMáx© is a valid and accessible questionnaire to estimate CRF expressed as VO2peak in clinical practice and shows substantial improvement compared to currently used questionnaires.